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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLL
All Species:
27.58
Human Site:
Y473
Identified Species:
55.15
UniProt:
Q9UGP5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UGP5
NP_037406.1
575
63482
Y473
E
N
G
Q
Q
Q
K
Y
L
G
V
C
R
L
P
Chimpanzee
Pan troglodytes
XP_507992
575
63394
Y473
E
N
G
Q
Q
Q
K
Y
L
G
V
C
R
L
P
Rhesus Macaque
Macaca mulatta
XP_001110483
575
63575
Y473
E
N
G
Q
Q
Q
K
Y
L
G
V
C
R
L
P
Dog
Lupus familis
XP_850651
576
63314
Y474
E
N
G
Q
Q
Q
K
Y
L
G
V
C
R
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXE2
573
62924
Y471
E
N
G
Q
Q
Q
K
Y
L
G
V
C
R
L
P
Rat
Rattus norvegicus
Q5RKI3
573
62383
Y471
E
N
G
Q
Q
Q
K
Y
L
G
V
C
R
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511409
1156
126349
D487
R
E
V
T
R
C
Y
D
G
P
V
P
K
G
T
Chicken
Gallus gallus
XP_001232209
575
63775
Y473
D
N
G
D
Q
K
K
Y
L
G
V
C
R
L
P
Frog
Xenopus laevis
O57383
334
38275
L241
K
F
M
G
V
C
Q
L
P
C
E
S
D
Q
D
Zebra Danio
Brachydanio rerio
Q6DRD3
336
38547
E243
G
V
C
Q
L
Q
K
E
K
E
E
E
E
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785226
410
45521
T317
S
A
I
P
G
I
G
T
K
M
A
D
K
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172522
529
59569
P435
Y
F
G
L
C
T
Y
P
G
Q
E
L
R
R
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97
85.4
N.A.
82.4
82.4
N.A.
33.8
66.7
22
21.5
N.A.
N.A.
N.A.
N.A.
20
Protein Similarity:
100
99.6
98.4
91.3
N.A.
88.3
88.8
N.A.
40.2
78
36.7
36.1
N.A.
N.A.
N.A.
N.A.
37.7
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
80
0
20
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
93.3
13.3
20
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
0
0
0
9
0
0
0
0
% A
% Cys:
0
0
9
0
9
17
0
0
0
9
0
59
0
0
0
% C
% Asp:
9
0
0
9
0
0
0
9
0
0
0
9
9
0
9
% D
% Glu:
50
9
0
0
0
0
0
9
0
9
25
9
9
9
9
% E
% Phe:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
67
9
9
0
9
0
17
59
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
9
0
0
0
0
0
0
0
9
0
% I
% Lys:
9
0
0
0
0
9
67
0
17
0
0
0
17
0
0
% K
% Leu:
0
0
0
9
9
0
0
9
59
0
0
9
0
59
9
% L
% Met:
0
0
9
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
59
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
9
0
0
0
9
9
9
0
9
0
0
59
% P
% Gln:
0
0
0
59
59
59
9
0
0
9
0
0
0
9
0
% Q
% Arg:
9
0
0
0
9
0
0
0
0
0
0
0
67
9
9
% R
% Ser:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% S
% Thr:
0
0
0
9
0
9
0
9
0
0
0
0
0
0
9
% T
% Val:
0
9
9
0
9
0
0
0
0
0
67
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
17
59
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _